Rafael Nadal and Andy Roddick advanced into the last eight of the Miami Masters.
Marat Safin battled to 6-3, 7-6 first round win over Igor Kunitsyn at the Legg Mason Tennis Classic.
World number one Rafael Nadal needed two tie-breaks to outlast Stanislas Wawrinka 7-6 7-6 at the Sony Ericsson Open on Tuesday, the Spaniard's win completing an ominous march into the quarter-finals for the top seeds.
The world number one went down to Spain's Albert Costa in the second round of the Rome Masters.
Argentine Guillermo Coria and Russia's Nikolay Davydenko are front-runners for the last two slots at the end-of-season Masters Cup.
Roger Federer will open his bid for a third successive Masters Cup title, and a fifth in all, against Gilles Simon after being grouped with the Frenchman in Wednesday's draw for the $4.45 million (2.8 million pounds) tournament. The Swiss is top seed in the absence of Spain's world number one Rafael Nadal, whose withdrawal through injury allowed Simon to take his place in the season-ending event for the top eight men in the world.
Jo-Wilfried Tsonga won his maiden Masters Series event when he beat Argentine David Nalbandian 6-3, 4-6, 6-4 in the final of the Paris Masters on Sunday to clinch the last qualifying spot for the season's finale in Shanghai. The 23-year-old Frenchman joined Rafael Nadal, Roger Federer, Novak Djokovic, Andy Murray, Nikolay Davydenko, Andy Roddick and Juan Martin del Potro as the players who qualified for the Masters Cup, which will start on Nov. 9.
Coco Gauff became the first American to win a US Open singles title since Sloane Stephens in 2017.
The world number one looked unstoppable as he battered Berdych 7-6, 6-1 to set up last four clash with home favourite Andy Murray before Novak Djokovic crushed a jaded Andy Roddick 6-2, 6-3 in the final Group A action to book a meeting with Roger Federer.
Wimbledon will herald a new men's champion and for the four players left in the draw, the moment has been a long time coming.
The rising stars of men's tennis will slug it out in the third round on the show courts on Friday.
Russia, losing finalists to the US last year, also went 2-0 up on day one, helped by misfortune in the Serbian camp.
Germany's Tommy Haas came from a set down to upset 11th-seeded Andy Murray 2-6, 7-5, 6-3 in Wednesday's fourth round and maintain his impressive run at the Pacific Life Open.
Somdev Devvarman's French Open adventure ended on Sunday when he lost a topsy-turvy first round match against Swiss Marco Chiudinelli.
Defending champion David Nalbandian beat top seed Andy Roddick 7-5 7-5 in the Swiss Indoors semi-finals.
The British ace was beaten by defending champion David Nalbandian in the quarter-finals of the Swiss Indoors.
List of US Open men's singles champions since tennis turned professional in 1968.
Here is a quick glance of all the highs and lows from Nadal's stupendous career:
With Andy Roddick retired, Mardy Fish unavailable and Spain apparently unbeatable at home on clay, the United States look distant second favourites when the two nations clash in the Davis Cup semi-final in Gijon starting on Friday.
Fernando Gonzalez claimed a 6-4, 3-6, 7-6 victory over third-seeded American Andy Roddick to reach the final of the Vienna Open.
Rafael Nadal battled past German Tommy Haas 7-6, 6-3 to reach the Cincinnati Masters quarter-finals.
Andy Murray passed his first test under new coach Brad Gilbert, beating Ramon Delgado 6-4, 6-3 in the second round.
Andy Murray and Rafael Nadal made it to the final of the Indian Wells tournament after victories over Roger Federer and Andy Roddick respectively.
Britain's Andy Murray has said he wants American tennis guru Brad Gilbert to be the coach to take him to the next level.
List of Wimbledon men's singles champions since 1922.
Serena Williams, brimming with confidence and self-belief with every match she plays, stormed into the semi-finals of the US Open on Wednesday with a 6-1, 6-3 demolition of Ana Ivanovic.
Novak Djokovic and Serena Williams, two players who have tasted the wrath of the New York crowd, begin their title campaigns with first-round matches at the US Open on Tuesday.
One magical point from Roger Federer capped an exhilarating first day at the US Open on Monday as a host of former champions each took their turn in the Flushing Meadows spotlight.
In fine fettle after a month-long rest, Roger Federer is ready to get his clay season underway and continue his bid to recapture the World No 1 ranking from Novak Djokovic.
The Swiss top seed begins his quest for a record-equalling fifth consecutive men's singles title against Teimuraz Gabashvili, while second seed Rafael Nadal meets American Mardy Fish.
Andre Agassi and Andy Roddick stayed on course for an all-American U.S. Open final.
The Swiss maestro beat beating Andy Roddick in the final to capture his ninth Grand Slam singles crown.
There's no American man in the top 10 in the ATP rankings issued on Monday - the first such instance since the rankings were introduced in 1973.